A landmark study titled "Functional Recovery Induced by KCC2-Enabled Relay Pathways in Completely Injured Spinal Cords in Adult Rats" has been published in the renowned international journal Proceedings of the National Academy of Sciences of the United States of America (PNAS). This groundbreaking research was conducted jointly by Academician Gu Xiaosong and Professor Yu Bin from our university's Key Laboratory of Neuroregeneration, in collaboration with Professor Wang Xuhua's team at Zhejiang University.

For years, "functional recovery after complete spinal cord transection" has been regarded as one of the most challenging problems in neural regeneration. Traditional views held that neural pathway reconstruction after complete spinal cord rupture was nearly impossible, making motor function recovery unattainable. The PNAS-published study by Academician Gu Xiaosong's team has, for the first time in adult rat models with complete spinal cord injury, successfully restored neural signal transmission across the injury site and achieved significant improvement in hindlimb motor function through a multimodal combined strategy.

https://news.ntu.edu.cn/2025/1217/c8062a283518/page.htm